Organic synthesis, supramolecular chemistry, chemical biology and more. On average get a first decision in 12 days for Communications and 18 days for Papers. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-organic chemistry 1 pdf physical organic chemistry, medicinal chemistry or natural products.
More details about key areas of our scope are below. In all cases authors should include in their article clear rational for why their research has been carried out. We welcome important research in all areas of organic synthesis, including studies on small organic molecules and biomolecules, and studies that report purely synthetic work without biological data. Total or multistep syntheses should report new or improved strategies or methods, or a more efficient route to the target compound.
Methodology studies should show a significant improvement on known methods. Research that extends known methodology to a different class of compounds is generally not suitable, unless that class is significantly different in scope to previously reported methodology. We welcome studies that report new models of reactivity, selectivity, bonding or structure, or new computational methods and have relevance for the design of subsequent experiments. That relevance should be clearly justified in the paper.